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A History of Lab Leaks

Madison and Maycee Holmes

December 17, 2025

Christof Plothe, D.O., and head researcher for the World Council for Health exposes multiple leaks of dangerous pathogens from biolabs in the past 100 years.

References Cited:

BBC. (2007, September 7). Foot-and-mouth leak ’caused by pipe’. BBC News. http://news.bbc.co.uk/2/hi/uk_news/6982590.stm

Bloom, J. D., Chan, Y. A., Baric, R. S., Bjorkman, P. J., Cobey, S., Deverman, B. E., … & Relman, D. A. (2021). Investigate the origins of COVID-19. Science, 372(6543), 694-694.

Chan, Y. A., Zhan, S. H., Moradi, P. V., Mordecai, G. J., & Nekrutenko, A. (2020). A tale of two hypotheses: Genetics and lab origins of SARS-CoV-2. The Yale Journal of Biology and Medicine, 93(4), 593.

Furmanski, M. (2014). Laboratory escapes and “self-fulfilling prophecy” epidemics. Center for Arms Control and Non-Proliferation.

Herby, J., Jonung, L., & Hanke, S. H. (2022). *A literature review and meta-analysis of the effects of lockdowns on COVID-19 mortality*. Studies in Applied Economics, The Johns Hopkins Institute for Applied Economics.

Jefferson, T., Dooley, L., Ferroni, E., Al-Ansary, L. A., van Driel, M. L., Bawazeer, G. A., … & Conly, J. M. (2023). Physical interventions to interrupt or reduce the spread of respiratory viruses. Cochrane Database of Systematic Reviews, (1).

Nelson, M. I., Simonsen, L., Viboud, C., Miller, M. A., & Holmes, E. C. (2008). The origin and global emergence of adamantane-resistant A/H3N2 influenza viruses. Virology, 388(2), 270-278.

Nordström, P., Ballin, M., & Nordström, A. (2022). Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and the oldest old: A nationwide, retrospective cohort study in Sweden. The Lancet Regional Health–Europe, 21.

ScienceFiles. (2025, Dezember 6). LabLeak: Wie viele Pathogene gäbe es ohne BSL-Labore nicht? Kurze Geschichte der “Laborunfälle”.

Weaver, S. C., Salas, R., Rico-Hesse, R., Ludwig, G. V., Oberste, M. S., Boshell, J., & Tesh, R. B. (1999). Re-emergence of epidemic Venezuelan equine encephalomyelitis in South America. The Lancet, 354(9184), 1357-1360.

Wertheim, J. O. (2010). The re-emergence of H1N1 influenza virus in 1977: a cautionary tale for estimating divergence times using biologically unrealistic sampling dates. PLoS One, 5(6), e11184.


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1 Comments

  1. Alan Church on December 19, 2025 at 7:26 am

    Excellent presentation. I did not realise how long this manipulation of viruses has been going on. Curiously, the WHO hasn’t denounced Gain of Function research.

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